| 发明名称 |
ACID DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS |
| 摘要 |
Compounds of formula I and II, or pharmaceutically-acceptable salts thereof , are useful as inhibitors of Factor VIIa, Factor IXa, Factor Xa, Factor FXIa, tryptase, and urokinase, wherein ring B is phenyl or pyridyl, L is a linker, and R1 R27, W, Z1 , and Z2 are as defined in the specification. |
| 申请公布号 |
WO0237937(A2) |
申请公布日期 |
2002.05.16 |
| 申请号 |
WO2001US49952 |
申请日期 |
2001.11.07 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;BISACCHI, GREGORY, S.;SUTTON, JAMES, C., JR.;WU, SHUNG, C. |
发明人 |
BISACCHI, GREGORY, S.;SUTTON, JAMES, C., JR.;WU, SHUNG, C. |
| 分类号 |
A61K31/192;A61K31/402;A61K31/4458;A61K31/4545;A61K31/55;A61K45/00;A61K45/06;A61P7/02;A61P29/00;A61P37/00;C07C257/18;C07D207/16;C07D211/60;C07D223/06;C07D401/12 |
主分类号 |
A61K31/192 |
| 代理机构 |
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