| 摘要 |
medicine, pharmacy, pharmacology. SUBSTANCE: invention relates to the noncarbonated, pressed, solid, dosed form designated for peroral usage. The dosed form comprises ibuprofen active component and a carrier comprising extrudable filling agent in common with disintegrator that contains ibuprofen medicinal component in the amount 35 wt.-% or more of the dosed form characterized in that a carrier has alkaline metal carbonate or hydrocarbonate additionally. Invention proposes also the use and a method of producing the noncarbonated, solid dosed form of the proposed agent. Invention provides the sufficient strength and shows indices providing the rapid release of drug. EFFECT: improved properties of dosed form. 21 cl, 2 dwg, 31 ex |
