发明名称 Polymorph of salt of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]-benzyl]thiazolidine-2,4-dione with maleic acid
摘要 <p>A polymorphic form of 5-Ä4-Ä2-(N-methyl-N-(2-pyridyl)amino)ethoxyÜbenzylÜthiazolidine-2,4-dione, maleic acid salt (the "Polymorph") characterised in that it provides: (i) an infra red spectrum containing peaks at 1763, 912, 856 and 709 cm<-1>; and/or (ii) a Raman spectrum containing peaks at 1762, 1284, 912 and 888 cm<-1>; and/or (iii) a solid-state <13>C nuclear magnetic resonance spectrum containing peaks at 111.0, 113.6, 119.8, 129.1, 130.9, 131.8, 134.7, 138.7, 146.5, 152.7, 157.5, 169.5, 171.0, 178.7 ppm; and/or (iv) an X-ray powder diffraction (XRPD) pattern which gives calculated lattice spacings at 5.87, 5.30, 4.69, 4.09, 3.88, 3.61, 3.53 and 3.46 Angstroms; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compund in medicine.</p>
申请公布号 CZ20013800(A3) 申请公布日期 2002.04.17
申请号 CZ20010003800 申请日期 2000.04.19
申请人 SMITHKLINE BEECHAM PLC;SMITHKLINE BEECHAM (CORK) LIMITED 发明人 BLACKLER PAUL DAVID JAMES;BROWNE CHRISTINE MARIE;COAKLEY TIMOTHY G.;GILES ROBERT GORDON;MORRISSLEY GILLIAN
分类号 A61K31/4439;A61P3/10;C07D417/12;(IPC1-7):C07D417/12;A61K31/442 主分类号 A61K31/4439
代理机构 代理人
主权项
地址