发明名称 |
PHARMACEUTIC AGENT FOR USE AGAINST URINE INCONTINENCE AND METHOD OF OBTAINING (S)-DESETHYLOXYBUTININE |
摘要 |
A method for treating urinary incontinence while avoiding concomitant liability of adverse effects associated with racemic oxybutynin is disclosed. The method comprises administering a therapeutically effective amount of (S)-oxybutynin, (S)-desethyloxybutynin or a pharmaceutically acceptable salt thereof, substantially free of the corresponding R enantiomer. Pharmaceutical compositions in the form of tablets and transdermal devices comprising (S)-oxybutynin or (S)-desethyloxybutynin and an acceptable carrier are also disclosed, as is a synthesis of desethyloxybutynin. |
申请公布号 |
PL182768(B1) |
申请公布日期 |
2002.02.28 |
申请号 |
PL19960321498 |
申请日期 |
1996.01.25 |
申请人 |
SEPRACOR,INC. |
发明人 |
ABERG GUNNAR;MC CULLOUGH JOHN R.;FANG YUE |
分类号 |
A61K31/00;A61K9/66;A61K31/215;A61K31/216;A61P13/00;C07C69/738;C07C211/28 |
主分类号 |
A61K31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|