发明名称 |
NOVEL ENANTIOMERIC COMPOUNDS FOR TREATMENT OF CARDIAC ARRHYTHMIAS AND METHODS OF USE |
摘要 |
The subject invention pertains to novel enantiomerically pure compounds, and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns a method of making and purifying the compounds. The enantiomerically purified compounds, and compositions of these compounds, exhibit unexpectedly distinct and advantageous characteristics, such as a markedly superior ability to reduce or inhibit ventricular premature beats, as compared to racemic mixtures of the compounds.
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申请公布号 |
WO0129018(A3) |
申请公布日期 |
2001.11.29 |
申请号 |
WO2000US28636 |
申请日期 |
2000.10.13 |
申请人 |
ARYX THERAPEUTICS;DRUZGALA, PASCAL;MILNER, PETER, G. |
发明人 |
DRUZGALA, PASCAL;MILNER, PETER, G. |
分类号 |
C07D307/80;A61K31/343;A61P9/04;A61P9/06;A61P9/10;C07D307/54;(IPC1-7):C07D307/54 |
主分类号 |
C07D307/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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