COMBINED INTERFERON ALFA AND LIPOSOMAL-ENCAPSULATED ALL-TRANS RETINOIC ACID, INCLUDING PREPARATION AND USE

摘要

Alfa interferon ( alpha -IFN or alpha-interferon) and liposomal all-trans retinoic acid is useful in cancer treatment with particular reference to renal cancer. Optionally, a regimen of alpha -interferon from about 3 to about 5 million units sc daily and liposomal all-trans retinoic acid at from a bout 15 mg/m<2> to about 90mg/m<2>, or about 140mg/m<2>, or about 300mg/m<2> or more. Dosage periodicity of about three times per week for both drugs in about 8 week cycles is useful.