发明名称 2,3-methano-amino acid compounds
摘要 Compound of formula (I):wherein:n represents 2 or 3,R1 represents optionally substituted alkyl, cycloalkyl or optionally substituted phenyl,R2 represents amino, optionally substituted amidino, optionally substituted guanidino or optionally substituted isothioureido,Ar represents aryl or heteroaryl,X1 represents hydroxy or optionally substituted amino,isomers thereof, and also salts thereof with a pharmaceutically acceptable acid or base, and whichmedicinal products containing the same/are useful as trypsin-related serine protease inhibitors.
申请公布号 US6288077(B1) 申请公布日期 2001.09.11
申请号 US20000561618 申请日期 2000.05.02
申请人 ADIR ET COMPAGNIE 发明人 DE NANTEUIL GUILLAUME;GLOANEC PHILIPPE;VERBEUREN TONY;RUPIN ALAIN
分类号 C12N9/99;A61K31/401;A61K31/403;A61K31/4427;A61K31/4439;A61K38/55;A61P7/02;A61P9/00;A61P43/00;C07D209/52;C07D221/04;C07D401/12;C07K5/02;(IPC1-7):A61K31/435;A61K31/40 主分类号 C12N9/99
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