| 发明名称 |
Radioimmunotherapy of lymphoma using anti-CD20 antibodies |
| 摘要 |
Methods for the treatment of lymphoma by adminstration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
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| 申请公布号 |
US6287537(B1) |
申请公布日期 |
2001.09.11 |
| 申请号 |
US19980087392 |
申请日期 |
1998.05.29 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;COULTER PHARMACEUTICAL, INC. |
发明人 |
KAMINSKI MARK S.;BUTCHKO GREGORY M.;GLENN STEPHAN D.;WAHL RICHARD L. |
| 分类号 |
A61K38/00;A61K38/19;A61K51/10;C07K14/52;C07K16/22;C07K16/28;C12P21/08;G01N33/574;(IPC1-7):A61K51/00;A61K39/395;C07K16/00 |
主分类号 |
A61K38/00 |
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