METHODS AND COMPOSITIONS FOR REDUCING IMMUNE RESPONSE

摘要

The present invention provides an apparatus and method to diminish the pre- existing immune response to the administration of a therapeutic virus by the selective elimination of antiviral antibodies from the serum. The present invention provides a chromatographic material for the elimination of such antibodies. The invention further provides plasmapheresis apparatus comprisi ng this material. The invention further provides methods for the employment of such apparatus as part of therapeutic treatment regiments.