发明名称 |
Evolution and use of enzymes for combinathorial and medicinal chemistry |
摘要 |
This invention provides libraries of recombinant derivatizing enzymes that are useful for biocatalytic synthesis of derivatives oforganic molecules, including lead compounds for pharmaceutical use. The recombinant derivatizing enzymes catalyze reactions such as modification or replacement of functional groups on the organicmolecules, or addition of chemical moieties onto preexisting functional groups. The use of recombinant enzyme libraries enables one to obtain enzymes that catalyze the formation of organic molecule derivatives that could not otherwise be made using only naturally occurring enzymes. |
申请公布号 |
AU7057500(A) |
申请公布日期 |
2001.03.13 |
申请号 |
AU20000070575 |
申请日期 |
2000.08.11 |
申请人 |
MAXYGEN, INC.;LU LIU |
发明人 |
CLAUS KREBBER;S. CHRISTOPHER DAVIS;STEPHEN DEL CARDAYRE;SERGEY A. SELIFONOV;RUSSELL HOWARD |
分类号 |
C12N15/09;C12N9/00;C12N15/52;C12P1/00;C12P19/62;C12Q1/00;C12Q1/02;C40B40/02;C40B50/06;H01J49/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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