摘要 |
PROBLEM TO BE SOLVED: To obtain a new compound having excellent antibacterial activities even against an acid-fast bacterium resistant to rifampicin, kanamycin or the like, and useful as an antibacterial agent. SOLUTION: This new compound is represented by the formula. The compound of the formula is obtained by culturing a microorganism belonging to the genus Nocardia, and capable of producing a compound of the formula, [e.g. Nocardia sp. MK-703-102F1 strain (FERM P-16580)] in a medium comprising a carbon source such as glycerol; a nitrogen source such as a corn steep liquor, and the like, preferably at 25-30 deg.C, and collecting the compound of the formula from the cultured product. The compound of the formula has the following physicochemical properties: appearance: colorless powder; high resolution mass spectrometry (HRFAB MS: cation mode): experimental value: 456.3242 (M)+, and calculated value: 456.3240; specific rotation: [α]D25+85.4 deg. (c 0.63, MeOH); solubility: soluble in methanol and acetone, and insoluble in water.
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