| 发明名称 |
Anti-mitotic agents which inhibit tubulin polymerization |
| 摘要 |
PCT No. PCT/US98/04380 Sec. 371 Date Dec. 3, 1999 Sec. 102(e) Date Dec. 3, 1999 PCT Filed Mar. 6, 1998 PCT Pub. No. WO98/39323 PCT Pub. Date Sep. 11, 1998Methoxy and ethoxy substituted 3-aroyl-2-arylbenzo[b]thiophenes and benzo[b]thiophene analogues are described for use in inhibiting tubulin polymerization. The compounds' use for treating tumor cells is also described.
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| 申请公布号 |
US6162930(A) |
申请公布日期 |
2000.12.19 |
| 申请号 |
US19990380429 |
申请日期 |
1999.12.03 |
| 申请人 |
BAYLOR UNIVERSITY |
发明人 |
PINNEY, KEVIN G.;PETTIT, GEORGE R.;MOCHARLA, VANI P.;MEJIA, MARIA DEL PILAR;SHIRALI, ANUPAMA |
| 分类号 |
C07C43/23;C07C45/30;C07C49/84;C07C205/37;C07C217/84;C07C247/16;C07D307/80;C07D333/56;C07D333/64;(IPC1-7):C07D333/56;C07D333/52;C07C41/00;C07C49/115 |
主分类号 |
C07C43/23 |
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