| 发明名称 |
NOVEL INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR- alpha MODULATORS, SYNTHESES OF SAID MODULATORS AND METHODS OF USING SAID MODULATORS |
| 摘要 |
Compounds are disclosed that have the chemical structure of Formula (II) and (IIB) and their produg esters and acid-addition salts, and that are useful as Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are useful in the treatment of various diseases, wherein the R groups are defined in the claims.
|
| 申请公布号 |
WO0073253(A1) |
申请公布日期 |
2000.12.07 |
| 申请号 |
WO2000US13202 |
申请日期 |
2000.05.12 |
| 申请人 |
NEREUS PHARMACEUTICALS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
PALLADINO, MICHAEL;THEODORAKIS, EMMANUEL, A. |
| 分类号 |
A61P3/10;A61K31/12;A61K31/16;A61K31/19;A61K31/215;A61P9/02;A61P11/02;A61P17/00;A61P27/16;A61P29/00;A61P31/06;A61P31/12;A61P35/00;A61P37/06;C07C13/60;C07C33/14;C07C51/09;C07C61/29;C07C61/35;C07C62/32;C07C67/343;C07C67/347;C07C69/00;C07C69/753;(IPC1-7):C07C61/35;C07C69/757;C07C69/007;A61K31/22;A61K31/045;A61K31/015 |
主分类号 |
A61P3/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
