REMEDIES FOR NEUROPATHIC PAIN

摘要

Compounds represented by general formula (I) or salts thereof and medicinal compositions containing the same as the active ingredient: wherein A represents, for example, phenyl substituted by R<1> and R<2>, unsubstituted furyl or unsubstituted thienyl (wherein R<1> represents, for example, hydrogen, fluoro, chloro, trifuloromethyl, nitro, cyano or methyl; and R<2> represents, for example, hydrogen); R<3> represents, for example, hydrogen or methyl; R<4> represents, for example, hydrogen or methyl; R<5> represents ethoxy or iso-propoxy; X represents -CH(OH)- or methylene; and Z represents, for example, a single bond or optionally hydroxylated methylene. These compounds can be orally administered as remedies for neuropathic pain and exhibit excellent effect while showing littLe side effects.