发明名称 DIHYDROBENZODIOXINE CARBOXAMIDE AND KETONE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS
摘要 This invention relates to certain 5-HT4 receptor antagonist compounds represented by Formula (I), wherein Z is represented by formula (A) or (B), wherein R1, R2, R3, R4 and R5 and the other substituents are as defined in t he specification; and the individual isomers, racemic or non-racemic mixtures o f isomers, and pharmaceutically acceptable salts or hydrates thereof. The invention further relates to pharmaceutical compositions containing such compounds and for their use as therapeutic agents.
申请公布号 CA2340952(A1) 申请公布日期 2000.03.23
申请号 CA19992340952 申请日期 1999.09.01
申请人 F. HOFFMANN-LA ROCHE AG 发明人 JAHANGIR, ALAM;CLARK, ROBIN DOUGLAS
分类号 A61K31/443;A61K31/453;A61K31/496;A61K31/5377;A61P43/00;C07D405/06;C07D405/12;C07D405/14;(IPC1-7):C07D405/14;C07D413/14;A61K31/35;A61K31/445;A61K31/495 主分类号 A61K31/443
代理机构 代理人
主权项
地址