ANTIBIOTIC PROTEIN AND METHOD OF PRODUCTION

摘要

The invention provides an antibiotic protein having the properties of a native Bacillus subtilis TasA protein. The invention also provides a method of translocating a desired protein across a membrane by expressing the desired protein as a fusion with a SipW recognition sequence in a membrane-bound genetic expression system. When a sporulating bacterium is employed as the membrane-bound expression system, the domain consisting of the desired protein is cleaved from the fusion protein and secreted into the resultant spores.