| 摘要 |
Remedies having an enhanced efficacy against solid tumor, rheumatoid arthritis, diabetic retinopathy, premature retinopathy, psoriasis, etc. comprising a combination of a substance inhibiting signal transduction mediated by a human VEGF receptor Flt-1 with a substance inhibiting signal transduction mediated by a human VEGF receptor KDR, which are useful in diagnosing or treating diseases worsening with abnormal neovascularization, for example, proliferation or metastasis of solid tumor, arthritis in rheumatoid arthritis, diabetic retinopathy, premature retinopathy, psoriasis, etc.
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