| 摘要 |
Spiro compounds represented by general formula (I), wherein A, R<2>, R<3>, R<4>, R<5>, R<6> and n are each as defined in the specification; which exert an AP-1 activity inhibitory effect. Owing to this effect, these compounds are useful as remedies/preventives for autoimmune diseases which inhibit the expression of various genes and show little side effect.
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| 申请人 |
TOYAMA CHEMICAL CO., LTD.;CHAKI, HISAAKI;AIKAWA, YUKIHIKO;MIYAJIMA, MIKAKO;TAKAKURA, TADAKAZU;NISHIO, MORIHIRO;KURODA, HIROSHI;TANAKA, KEIICHI;KAJITA, TETSUYA;HIRONO, SHUICHI;SHIOZAWA, SHUNICHI |
发明人 |
CHAKI, HISAAKI;AIKAWA, YUKIHIKO;MIYAJIMA, MIKAKO;TAKAKURA, TADAKAZU;NISHIO, MORIHIRO;KURODA, HIROSHI;TANAKA, KEIICHI;KAJITA, TETSUYA;HIRONO, SHUICHI;SHIOZAWA, SHUNICHI |
