METHODS AND APPARATUS FOR HIGH THROUGHPUT PLATE TO PLATE OR PLATE TO MEMBRANE TRANSFER

摘要

Techniques for high throughput parallel separation, filtration and plate to plate transfer are described. Cells, proteins, chemical compounds and the like are being developed in multiwell, small volume well plates (240, 250), such as 1536-well plates having wells of a volume on the order of 1 mu 1. A mechanism (200) for clamping such plates together so that the wells will be aligned allows rapid separation or transfer by simply centrifuging the assembly. A membrane (230) may be clamped between the plates. Alternatively, a membrane may replace one of the plates. Centrifuge dependent and independent designs are described.