发明名称 |
Device for aerosolized delivery of peptide drugs |
摘要 |
A method of treating human patients is provided by the intrapulmonary delivery of a pharmaceutically active peptide formulation. The formulation is automatically released in an aerosolized form from a hand-held, self-contained, portable device comprised of a means for automatically releasing a measured amount of drug into the inspiratory flow path of a patient in response to information obtained from a means for measuring the inspiratory flow rate and determining the inspiratory volume of a patient. Reproducible dosing is obtained by providing for automatic release at the same inspiratory flow rate and inspiratory volume each time drug is released. The device includes a timer to enable a patient to take a drug at the same time each day. Further, overadministration of hormone formulations is avoided by providing a pre-programmed microprocessor designed to avoid overdosing. |
申请公布号 |
AU708269(B2) |
申请公布日期 |
1999.07.29 |
申请号 |
AU19960041966 |
申请日期 |
1995.10.27 |
申请人 |
ARADIGM CORPORATION |
发明人 |
LESTER J LLOYD;PETER M LLOYD;REID M RUBSAMEN;JEFFREY A SCHUSTER |
分类号 |
A61K38/22;A61J7/04;A61K38/23;A61M11/00;A61M15/00;A61M16/00;A61M16/10;A61P29/00;A61P35/00;A61P43/00 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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