The present invention is directed toward radiolabeled farnesyl-protein transferase inhibitor compounds which are useful to label FPTase in assays, whether cell-based, tissue-based or in whole animal. The tracers can also be used in competitive binding assays to obtain information on the interaction of unlabeled FTIs with FPTase.
申请公布号
WO9900654(A3)
申请公布日期
1999.03.25
申请号
WO1998US09853
申请日期
1998.05.11
申请人
MERCK & CO., INC.;BURNS, HUGH, D.;ENG, WAI-SI;GIBSON, RAYMOND, E.
