Substances of polypeptide nature useful in human therapy

摘要

Substances of polypeptide nature are obtainable by extraction with HClO4 and 3M KCl from animal tissue homogenates. The substances have the characteristics of (a) molecular weights ranging from 10,000 to 50,000 daltons (by polyacrylamide gel electrophoresis); (b) are capable of inducing the formation of antibodies which specifically bind in vivo or in vitro antigens which are present in human tumoral cells, when administered to different animal species; (c) are capable of decreasing or inhibiting pain; (d) induce an effect of cell lysis; and (e) inhibit or slow tumor growth, when administered to humans affected by malignant tumors of different kinds.