发明名称 |
HOMOGENOUS MICRODISPERSIONS OF FLUORINE COMPOUNDS FOR ADMINISTERING PHARMACEUTIC AGENTS |
摘要 |
A method for preparing a pharmaceutical microdispersion exhibiting enhanced bioavailability, including the steps of providing a thermodynamically stable pharmaceutical composition comprising at least one lipophilic pharmaceutical agent incorporated in a physiologically acceptable liquid carrier, the liquid carrier comprising one or more lipophilic solvents such as fluorochemicals and preferably at least one nonfluorinated co-solvent, and combining the stable pharmaceutical composition with an amount of at least one miscible diluent sufficient to initiate phase separation of the lipophilic pharmaceutical agent from the pharmaceutical composition wherein a microdispersion of the pharmaceutical composition is formed. Also disclosed are microdisperse pharmaceutical compositions and kits for forming such compositions.
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申请公布号 |
PL323829(A1) |
申请公布日期 |
1998.04.27 |
申请号 |
PL19960323829 |
申请日期 |
1996.06.05 |
申请人 |
ALLIANCE PHARMACEUTICAL CORP |
发明人 |
TREVINO LEO A.;DELLAMARY LUIS A.;TARARA THOMAS E.;WEERS JEFFRY G.;RANNEY HELEN M. |
分类号 |
A61K9/10;A61K9/00;A61K9/107;(IPC1-7):A61K9/00 |
主分类号 |
A61K9/10 |
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