发明名称 NEW COMPOUND WF15483, PRODUCTION AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To obtain the subject new compound manifesting an antifungal activity, capable of being used as a fungicide in the fields of a medicine, an agrochemical and a cleaning product and especially useful as a therapeutic agent for a fungal infections disease, etc., by culturing a WF15483 producing strain belonging to mold fungi in a medium. SOLUTION: This new compound WF15483 is two compound consisting of (A) WF15483A having an appearance of a colorless powder, a molecular formula of C60 H97 N15 O21 , 115-119 deg.C (decomposition) melting point, 1364.53 molecular weight [FAB-MS: m/z 1387 (M+Na)], solubilities of hardly soluble to water, methanol and acetonitrile, and insoluble to n-hexane, color development reactivities of positive in reactions with iodine vapor and cerium sulfate, pseudo positive in reactions to ninhydrin and ferric chloride and negative in reactions to Dragendorff's and Molische's and (B) WF15483B having similar appearance, solubilities, and color development reactions, a molecular formula of C59 H75 N15 O21 , 1350.50 molecular weight [FAB-MS; m/z 1373 (M+Na)], and obtained by culturing a mold fungus strain No.15483 (FERMBP-5526) in a medium.
申请公布号 JPH1080291(A) 申请公布日期 1998.03.31
申请号 JP19970140515 申请日期 1997.05.29
申请人 FUJISAWA PHARMACEUT CO LTD 发明人 HASHIMOTO MICHIMASA;TSURUMI YASUHISA;TAKASE SHIGEHIRO;KINO TORU;HASHIMOTO MASAHARU
分类号 C12P1/02;A61K36/06;A61P31/04;C07G11/00;C12N1/14;C12R1/645 主分类号 C12P1/02
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