| 发明名称 |
SPECIFIC INHIBITORS OF DNA METHYLTRANSFERASE ENZYME |
| 摘要 |
The invention provides novel mechanism-based inhibitors of DNA methyltransferase enzyme, and diagnostic and therapeutic uses for the same. The novel inhibitors according to the invention form stable, noncovalent complexes with DNA methyltransferase enzyme in a manner which is independent of S-adenosylmethionine.
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| 申请公布号 |
CA2256305(A1) |
申请公布日期 |
1997.11.27 |
| 申请号 |
CA19972256305 |
申请日期 |
1997.05.22 |
| 申请人 |
MCGILL UNIVERSITY |
发明人 |
SZYF, MOSHE;BIGEY, PASCAL |
| 分类号 |
A61K38/00;C07H21/00;C12N15/113;(IPC1-7):C07H21/00;A61K48/00;C12Q1/48;C12Q1/68;A61K31/70 |
主分类号 |
A61K38/00 |
| 代理机构 |
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