发明名称 USE OF 4-PHENYL-3,6-DIHYDRO-2H-PYRIDYL DERIVATIVES AS NMDA RECEPTOR SUBTYPE BLOCKERS
摘要 The present invention relates to the use of compounds of general formula (I) wherein R1 is hydrogen, halogen, lower alkyl or lower alkoxy; R2 is hydrogen; R3 is hydrogen, amino, ureido, lower alkylcarbonyl, lower alkylsulfonylamino, lower alkylcarbamoyl, carbamoyl, lower alkyloxycarbamoyl, lower alkylamino or R2 and R3 taken together are -(CH2)m-, X is methylene, hydroxymethylene, lower alkoxymethylene or carbonyl, n is 1 or 2 and m is 3 or 4; as well as pharmaceutically acceptable salts for the manufacture of medicaments for the control or treatment of diseases which represent therapeutic indications for NMDA receptor subtype specific blockers.
申请公布号 CA2248134(A1) 申请公布日期 1997.09.12
申请号 CA19972248134 申请日期 1997.02.27
申请人 F.HOFFMANN-LA ROCHE AG 发明人 HEITZ NEIDHART, MARIE-PAULE;MUTEL, VINCENT;TRUBE, GERHARD;FISCHER, GUENTHER;BOURSON, ANNE
分类号 C07D211/00;A61K31/44;A61K31/4418;A61P9/10;A61P25/14;A61P25/16;A61P25/28;A61P43/00;C07D211/70;(IPC1-7):A61K31/44 主分类号 C07D211/00
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