| 发明名称 |
Inhibitors of farnesyl-protein transferase |
| 摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras. |
| 申请公布号 |
AU2253097(A) |
申请公布日期 |
1997.08.22 |
| 申请号 |
AU19970022530 |
申请日期 |
1997.01.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
CHRISTOPHER J. DINSMORE;GEORGE D. HARTMAN |
| 分类号 |
C07D233/64;A61K31/00;A61K31/415;A61K31/4164;A61P43/00;C07D231/12;C07D233/54;C07D233/60;C07D233/61;C07D233/66;C07D233/90 |
主分类号 |
C07D233/64 |
| 代理机构 |
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