| 发明名称 |
Monoclonal antibodies reactive with a human atheroma associated antigen |
| 摘要 |
<p>The present invention relates to a naturally occurring, minimally modified LDL antigen which is present in human atherosclerotic lesions as well as in the serum of a high percentage of patients with coronary artery disease. The invention also comprises antibodies reactive with the antigen, hybridoma cell lines that produce the antibodies of the invention, and methods for using the antibodies in the diagnosis and treatment of atherosclerotic disease.</p> |
| 申请公布号 |
EP0433088(B1) |
申请公布日期 |
1997.06.18 |
| 申请号 |
EP19900313688 |
申请日期 |
1990.12.14 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BUMOL, THOMAS FRANK;MCEVOY, LESLIE MARGARET |
| 分类号 |
A61K39/00;A61K39/395;C07K1/22;C07K14/435;C07K14/775;C07K16/00;C07K16/18;C12N5/10;C12N5/20;C12N15/02;C12P21/08;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):C07K14/775;G01N33/92 |
主分类号 |
A61K39/00 |
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