发明名称 |
Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon |
摘要 |
In an improved process for the preparation of D- alpha -amino acids by the stereoselective conversion of racemic mixtures of 5-substituted hydantoins with an enzymatic system produced by a microorganism, the improvement consists in the fact that a microorganism is used transformed with the plasmid pSM700 cultivated at a temperature of between 20 DEG C and 28 DEG C. The use of this microorganism allows an improvement in the expression of the enzymatic system and an increase in the conversion rate of the racemic hydantoin to D- alpha -amino acid. <IMAGE> |
申请公布号 |
EP0775748(A2) |
申请公布日期 |
1997.05.28 |
申请号 |
EP19960117455 |
申请日期 |
1996.10.31 |
申请人 |
ENIRICERCHE S.P.A. |
发明人 |
GRIFANTINI, RENATA;GALLI, GIULIANO;GRANDI, GUIDO;CARPANI, GIOVANNA |
分类号 |
C12N15/09;C07B43/04;C07H21/04;C12N1/21;C12N1/38;C12N9/80;C12P13/04;C12P41/00;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|