| 摘要 |
A spray-dried, granular powder comprising: (i) from about 50 % to about 99 % of a water-soluble carrier, (ii) from about 1 % to about 50 % of a hydrophobic silicone oil dispersed within the carrier, wherein the spray-dried powder has a volume average particle size in the range from about 20 .mu.m to about 500 .mu.m, the powder being prepared by spray-drying an aqueous dispersion of the silicone oil and the water-soluble carrier, characterised in that the silicone oil is present in the dispersion in the form of discrete droplets having a volume average droplet size in the range from about 0.5 .mu.m to about 20 .mu.m and that the ratio of the average spray-dried particle size to the average droplet size is at least about 2.5:1. The powder is dry, free-flowing and processable into a punched tablet or other compressed forms, yet efficiently delivers the silicone oil on subsequent dissolution in water.
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