发明名称 |
2-{2-{(2-hydroxyethyl)amino}ethyl}-5-{{2-methylamino)ethyl}amino}indazolo{4,3-gh}isoquinolin-6(2h)-one as antitumor agent |
摘要 |
PCT No. PCT/EP96/03935 Sec. 371 Date Jun. 22, 1998 Sec. 102(e) Date Jun. 22, 1998 PCT Filed Sep. 9, 1996 PCT Pub. No. WO97/10245 PCT Pub. Date Mar. 20, 1997The present invention relates to 2-[2-[(2-hydroxyethyl)amino]ethyl]-5-[[2-methylamino)ethyl]amino]indazolo[4,3-gh]isoquinolin-6(2H)-one and the pharmaceutically acceptable acid addition salts thereof, of formula (I). This compound has shown a high a antitumor activity. |
申请公布号 |
AU6988296(A) |
申请公布日期 |
1997.04.01 |
申请号 |
AU19960069882 |
申请日期 |
1996.09.09 |
申请人 |
BOEHRINGER MANNHEIM ITALIA S.P.A.;THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE |
发明人 |
ERNESTO MENTA;AMBROGIO OLIVA;SILVANO SPINELLI;PAUL KRAPCHO |
分类号 |
C07D211/08;A61K31/00;A61K31/435;A61K31/4353;A61K31/437;A61P35/00;C07D471/06 |
主分类号 |
C07D211/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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