发明名称 2-{2-{(2-hydroxyethyl)amino}ethyl}-5-{{2-methylamino)ethyl}amino}indazolo{4,3-gh}isoquinolin-6(2h)-one as antitumor agent
摘要 PCT No. PCT/EP96/03935 Sec. 371 Date Jun. 22, 1998 Sec. 102(e) Date Jun. 22, 1998 PCT Filed Sep. 9, 1996 PCT Pub. No. WO97/10245 PCT Pub. Date Mar. 20, 1997The present invention relates to 2-[2-[(2-hydroxyethyl)amino]ethyl]-5-[[2-methylamino)ethyl]amino]indazolo[4,3-gh]isoquinolin-6(2H)-one and the pharmaceutically acceptable acid addition salts thereof, of formula (I). This compound has shown a high a antitumor activity.
申请公布号 AU6988296(A) 申请公布日期 1997.04.01
申请号 AU19960069882 申请日期 1996.09.09
申请人 BOEHRINGER MANNHEIM ITALIA S.P.A.;THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE 发明人 ERNESTO MENTA;AMBROGIO OLIVA;SILVANO SPINELLI;PAUL KRAPCHO
分类号 C07D211/08;A61K31/00;A61K31/435;A61K31/4353;A61K31/437;A61P35/00;C07D471/06 主分类号 C07D211/08
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