Helicobacter antigens

摘要

The present invention provides an antigenic polypeptide protective against Helicobacter infection together with vaccines containing the polypeptide. The polypeptide has an amino acid sequence of an approximately 18 kDa outer membrane vesicle (OMV) antigen of a Helicobacter spp. such as H. pylori. Fragments of the polypeptide containing the protective epitope of the polypeptide are contemplated as are functionally equivalent variants of the polypeptide.