Method of inhibiting fibrosis

摘要

Disclosed is a method of inhibiting fibrosis in a human or animal subject afflicted with a fibrosing disorder. The method comprises administering to the subject an effective fibrosis-inhibiting amount of a compound of Formula (I): <IMAGE> (I) wherein: n is 1 or 2; R is selected from the group consisting of hydrogen, C1-C4 alkyl, hydroxy, amino, and nitro; and R' is selected from the group consisting of hydrogen and C1-C4 alkyl. or a pharmaceutically acceptable salt thereof. Preferred as a compound of Formula (I) is benzoic hydrazide. Pharmaceutical formulations and the use of compounds of Formula (I) for making the same are also disclosed.