SEQUENCES AMPLIFICATRICES, VECTEURS PORTANT CES SEQUENCES ET LEURS UTILISATIONS DANS DES COMPOSITIONS POUR L'EXPRESSION DE SEQUENCES NUCLEOTIDIQUES DANS DES CELLULES TRANSFECTEES, APPLICATIONS THERAPEUTIQUES ET VACCINALES

摘要

An amplifier sequence at least 90 % homologous with SEQ ID No. 1: TCTATAAATA X1X2X3GC Y1Y2Y3GG TATTTGGGGT TGGCAGCTGT T, wherein X1, X2 and X3, which are the same or different, may be independently C or G, C or G and C or A respectively; and Y1, Y2 and Y3, which are the same or different, may be independently T or C, C or G and T or C respectively, is disclosed. Said sequence may be included in an expression vector or sequence further containing a sequence coding for a protein and a promoter. Such sequences enable very strong amplification of the transcription of the gene coding for the protein.