发明名称 |
Homobidental, trifunctional linkers, method for their preparation and use in immunologically active conjugates |
摘要 |
Compound of the general formula <IMAGE> +TR (CONH)s(CH2)pCOOR wherein R is an ester-activating group, m and n are identical or different and 0-6, p=0, 2-4, and q and s=1, p=0 if s=0 and p=2-4 if s=1. The compound is novel and suitable for the reproducible coupling of immunological substances at a high yield.
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申请公布号 |
US5519142(A) |
申请公布日期 |
1996.05.21 |
申请号 |
US19940219469 |
申请日期 |
1994.03.29 |
申请人 |
BOEHRINGER MANNHEIM GMBH |
发明人 |
HOESS, EVA;HUBER, ERASMUS;MARKERT-HAHN, CHRISTINE;OFENLOCH-HAEHNLE, BEATUS |
分类号 |
C07D207/44;C07D207/452;G01N33/532;G01N33/535;G01N33/543;(IPC1-7):C07D401/14;C07D403/14 |
主分类号 |
C07D207/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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