Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use

摘要

The present invention provides substituted dibenzoxazepine compounds of Formula I: <IMAGE> which are useful as analgesic agents for the treatment of pain, and for the treatment of prostaglandin E2-mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin E2-mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.