发明名称 |
Anhydrous crystal of 4-carbamoyl-1-beta-D-ribofuranosyl imidazolium-5-olate |
摘要 |
<p>Anhydrous crystals of 4-carbamoyl-1- beta -D-ribofuranosyl imidazolium-5-oleate are disclosed. The crystals possess (1) water content of 0.5% by weight or less (the Karl Fisher method), and (2) specific IR spectrum absorption peaks in the neighborhoods of 3580, 1852, 1630, 1575, and 1554 cm<-><1>. They are stable against heat and high humidity conditions and can easily be manufactured by using ethanol. The compound has superior immuno-suppressing activity and is thus made into preparations for oral administration.</p> |
申请公布号 |
EP0428879(B1) |
申请公布日期 |
1996.03.13 |
申请号 |
EP19900120255 |
申请日期 |
1990.10.22 |
申请人 |
ASAHI KASEI KOGYO KABUSHIKI KAISHA |
发明人 |
OZEKI, SHINJI;NAKATSUGAWA, SHINICHI |
分类号 |
C07H19/052;(IPC1-7):C07H19/052;A61K31/70 |
主分类号 |
C07H19/052 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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