Prodn. of sub-lingual formulation of psoralen or analogue

摘要

Prodn. of a sublingually administered medicament, based on a psoralen, azapsoralen, tetracyclic psoralen, angelicin, pyrrolocoumarin or khellin as active agent (A), comprises: (1) processing (A) (pref. in micronised form with particle size 1-10 microns) in the presence of at least one auxiliary to give a medicament (pref. a soln. or suspension) with high (A) concn. (pref. up to 100 mg/g); and (2) mfg. the medicament.