WATER SOLUBLE NON-IMMUNOGENIC POLYAMIDE CROSS-LINKING AGENTS

摘要

The present invention relates to water-soluble nonimmunogenic polyamide cross-linking agents and their use to cross-link, polymerize, decorate, and conjugate proteins, polynucleotides and other biological substrates to form substantially nonimmunogenic water-soluble products. The present invention also relates to proteins, polynucleotides and other biological substrates which are cross-linked, conjugated, polymerized or decorated with water-soluble polyamides to form substantially nonimmunogenic products.