发明名称 |
CLEAR, CHEMICALLY MODIFIED COLLAGEN-SYNTHETIC POLYMER CONJUGATES FOR OPHTHALMIC APPLICATIONS |
摘要 |
CLEAR. CHEMICALLY MODIFIED COLLAGEN-SYNTHETIC POLYMER CONJUGATES FOR OPHTHALMIC APPLICATIONS Various forms of chemically modified collagen are covalently crosslinked with activated synthetic hydrophilic polymers to form optically clear biocompatible conjugates useful in a variety of medical applications, particularly in ophthalmic devices. The chemically modified collagen is in substantially nonfibrillar form at pH 7 and is preferably succinylated or methylated collagen. The synthetic hydrophilic polymer is preferably an activated polymeric glycol, most preferably, a di- or multifunctionally activated polyethylene glycol. Materials and devices formed with the chemically modified collagen-synthetic polymer conjugates have good optical clarity, mechanical strength, and moldability. 38
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申请公布号 |
CA2134744(A1) |
申请公布日期 |
1995.05.04 |
申请号 |
CA19942134744 |
申请日期 |
1994.10.31 |
申请人 |
COLLAGEN CORPORATION |
发明人 |
RHEE, WOONZA M.;RAO, PREMA R.;CHU, GEORGE H.;DELUSTRO, FRANK A. |
分类号 |
A61L27/00;A61F2/00;A61F2/06;A61K38/00;A61K47/48;A61L24/10;A61L26/00;A61L27/18;A61L27/20;A61L27/24;A61L27/26;A61L27/34;A61L27/44;A61L27/54;A61L29/04;A61L29/06;A61L29/16;A61L31/04;A61L31/10;A61L31/12;C07K14/495;C07K14/78;C08B37/08;C08H1/00;C08H1/06;C08L89/06;C09J189/06;(IPC1-7):C07K14/78;C07K17/08;A61F2/14 |
主分类号 |
A61L27/00 |
代理机构 |
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地址 |
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