发明名称 THIOCHROMAN ESTERS OF PHENOLS AND TEREPHTHALLATES HAVING RETINOID-LIKE ACTIVITY
摘要 Compounds of formula I in which: the R groups are independently hydrogen or lower alkyl, one of the R groups being attached to the thiochroman ring at the 6 or the 7 position; one of A and B is O or S and the other is -C(O)-,A being attached to the thiochroman ring at the 6 or 7-position, with one of the R groups being attached to the other of said 6 and 7 position; n is 0-5; and Z is H, an acid or acid derivative, an alcohol or alcohol derivative, acetal or acetal derivative or ketone or ketone derivative, or a pharmaceutically acceptable salt, have retinoid-like activity.
申请公布号 CA1334424(C) 申请公布日期 1995.02.14
申请号 CA19890604151 申请日期 1989.06.28
申请人 ALLERGAN, INC. 发明人 CHANDRARATNA, ROSHANTHA A. S.
分类号 A61K31/38;A61K31/382;A61P17/00;A61P31/00;A61P35/00;C07D335/06;(IPC1-7):C07D335/06 主分类号 A61K31/38
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