H2 ANTAGONIST-SUCRALFATE-ANTIFLATULENT COMBINATIONS

摘要

This invention relates to pharmaceutical compositions for use in the treatment and relief of indigestion, sour stomach, heartburn and other gastrointestinal disorders in mammals, including humans, by administering compositions comprising (i) an amount effective in the prevention and/or treatment and relief of gastrointestinal or esophagus disorders of an H2 antagonist selected from a compound of formula (I) and pharmaceutically acceptable salts, hydrates, stereoisomers or polymorphs thereof, and (ii) an amount effective in the promotion of healing of tissue damage or ulcers associated with excess secretion of gastric acid of a glucopyranoside compound or a therapeutically active stereoisomer thereof substantially free of its other inactive or less active stereoisomers or a pharmaceutically acceptable salt, hydrate, or polymorph thereof, and (iii) an antiflatulent effective amount of an antiflatulent.