HARP FAMILY GROWTH FACTORS, PREPARATION METHODS THEREFOR AND USES THEREOF

摘要

A peptide having a similar sequence to peptide HARP and a mass of 18 kD. The N-terminal end of said peptide has one of the following sequences: NH2-ALA-GLU-ALA-GLY-LYS-LYS-GLU-LYS-PRO-GLU-LYS-LYS; NH2-ALA-VAL-ASP-THR-ALA-GLU-ALA-GLY-LYS-LYS-GLU-LYS-PRO-GLU;LYS-LYS. Said peptide or fragments thereof may be prepared by a genetic engineering method wherein vectors carrying at least part of the cDNA of the extended form of peptide HARP are expressed then extracted. Various therapeutical uses are disclosed.