| 摘要 |
PCT No. PCT/FR93/00128 Sec. 371 Date Oct. 14, 1993 Sec. 102(e) Date Oct. 14, 1993 PCT Filed Feb. 8, 1993 PCT Pub. No. WO93/15708 PCT Pub. Date Aug. 19, 1993.A composition comprises in an aqueous dispersion phase, a dispersion of lipid vesicles that encapsulate an aqueous phase. The lipid vesicles are a lipid phase containing an ionic amphiphilic lipid or a nonionic amphiphilic lipid, or a mixture thereof, together with a compound having the formula <IMAGE> (I) wherein (a) W represents -CH2OH, -COOM or -(CH2)2-COOM, wherein M represents H, alkali metal or alkaline earth metal and X, Y, Z and V, each independently, represent hydrogen or hydroxyl, with the proviso that when W represents -CH2OH at least one of X, Y, Z or V represents hydroxyl, or (b) W represents -CH3 and X, Y, Z and V represent H or OH combined as shown in each line of the table below: - X Y Z V - OH OH OH OH - OH H OH OH - OH OH OH H - H OH OH OH - H OH OH H - H H OH OH - OH H OH H - |
