发明名称 |
Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation. |
摘要 |
The present invention relates to a novel pharmaceutical composition for the preparation of effervescent powders or tablets incorporating ibuprofen or one of its pharmaceutically acceptable salts as the active ingredient. This composition comprises: an effective amount of ibuprofen or one of its pharmaceutically acceptable salts; a pharmaceutically acceptable effervescent system comprising at least one alkaline carbonate and at least one organic acid, preferably in a sufficient amount to give a pH below about 8; and at least one pharmaceutically acceptable antioxidant in a sufficient amount to stabilize the ibuprofen. This composition has a remarkable stability both in powder form and in tablet form.
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申请公布号 |
FR2698788(A1) |
申请公布日期 |
1994.06.10 |
申请号 |
FR19920014851 |
申请日期 |
1992.12.09 |
申请人 |
UPSA LABORATOIRES |
发明人 |
BRU-MAGNIEZ NICOLE, FRANCOISE;CORDOLIANI JEAN-FRANCOIS, SIMON;THAUVIN GERARD, JACQUES;DROUIN JEHAN-YVES, PIERRE |
分类号 |
A61K9/14;A61K9/46;A61K31/19;A61K31/192;A61K47/02;A61K47/10;A61K47/12;A61K47/20;A61K47/22;A61K47/26;A61K47/30;A61P25/04;A61P29/00;(IPC1-7):A61K31/19 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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