发明名称 3,3'-DISUBSTITUTED-1,3-DIHYDRO-2H-PYRROLO[2,3-b]HETEROCYCLIC-2-ONE USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS OF MAN
摘要 Compounds of formula (I) have been shown to enhance the release of the neurotransmitters acetylcholine, dopamine and serotonin; and thus may be useful in the treatment of diseases of man where subnormal levels of this neurochemical are found such as in Alzheimer's disease and other conditions involving learning and cognition; and Parkinson's disease. The compounds of this invention can be described as shown in formula (I) where A is a heteroaromatic system.
申请公布号 WO9406793(A1) 申请公布日期 1994.03.31
申请号 WO1993US08563 申请日期 1993.09.16
申请人 THE DU PONT MERCK PHARMACEUTICAL COMPANY 发明人 WILKERSON, WENDELL, WILKIE
分类号 C07D487/04;A61K31/435;A61K31/495;A61K31/505;A61P25/00;A61P43/00;C07D471/04;C07D491/048;C07D495/04;C07D498/04;C07D513/04;(IPC1-7):C07D471/04 主分类号 C07D487/04
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