| 摘要 |
An isolating chamber (1) with an annular connector (5) defines an access opening with one dimension greater than that perpendicular thereto and with an internal wall (5A) of constant section to allow the hermetic sliding of successive closure pieces (7,7X) which have a closure membrane (14,14X), and an annular cutting device (9B) for the membrane and for another membrane joined thereto. Each transfer machine (3) has a passageways slot and a closure membrane (22). The two membranes are designed to adhere to each other during the joining up of the two confined volumes (1,3) and are cut by the annular cutting device (9B) to define a discoid (D) with two at least peripherally joined thicknesses. The discoid can be removed into one of the confined volumes to provide the passage between the two the confined volumes; a subsequent uncut closure piece (7X) can be installed in the connector (5) from the interior of the isolating chamber (1), in order to replace the previous closure piece (7) which thus can be removed.
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