| 摘要 |
PCT No. PCT/SE92/00692 Sec. 371 Date Apr. 11, 1994 Sec. 102(e) Date Apr. 11, 1994 PCT Filed Oct. 2, 1992 PCT Pub. No. WO93/06921 PCT Pub. Date Apr. 15, 1993.Particles, especially colloidal particles, comprising an interior phase of a non-lamellar reversed cubic, intermediate or hexagonal liquid crystalline phase, or a homogeneous L3 phase, and a surface phase of a lamellar crystalline or liquid crystalline phase, or an L3 phase. A method of preparing such particles by creating a local dispersible phase, within the homogeneous phase, preferably by means of a fragmentation agent, and fragmentating the homogeneous phase so as to form said surface phase. Several medical as well as non-medical uses of the particles referred to, e.g. as an antigen-presenting system, as a delivery system for anticancer, antifungal and antimicrobial drugs, and as carriers of nucleic acids or nucleotides. |
