Therapeutic murine monoclonal antibody

摘要

PCT No. PCT/AU89/00139 Sec. 371 Date Nov. 21, 1990 Sec. 102(e) Date Nov. 21, 1990 PCT Filed Mar. 31, 1989 PCT Pub. No. WO89/09234 PCT Pub. Date Oct. 5, 1989.The present invention relates to a monoclonal antibody which is broadly reactive with all normal human peripheral blood mononuclear cells and granulocyte, and to the hybridoma cell line which produces this monoclonal antibody. This monoclonal antibody is designated WM-65 and the hybridoma cell line is designated F56-1D5 (ECACC 89033001). This monoclonal antibody reacts with a previously unrecognized human leucocyte surface membrane antigen. The relative molecular mass of the antigen recognized by WM-65 is approximately 40-50 Kilodaltons.