SULFATED GLYCOLIPIDS, CONTAINING A GALACTOSE-3-0-SULFATE MOIETY, AND SPECIFIC CATCHERS THEREFOR FOR USE IN THE PROPHYLAXIS OR THERAPY OF PREDIABETES, DIABETES AND/OR ASSOCIATED COMPLICATIONS IN AN INDIVIDUAL

摘要

Methods for the treatment of prediabetes or diabetes in an individual comprise administering to the individual a therapeutically active agent comprising a glycolipid having a galactose-3-O-sulfate moiety capable of binding to islet cell antibodies. Methods of detecting or quantifying islet cell antibodies in a sample, methods for the detection of Langerhans islet cells, methods for monitoring the development of prediabetes, diabetes or symptoms thereof in an individual and methods for prophylactic treatment against the development of prediabetes or diabetes also involve the use of a glycolipid having a galactose-3-O-sulfate moiety.